amiloride hctz
(hyde droe klor oh THYE a zide and ER beh sar tan)
Avalide
What is the most important information I should know about HCTZ (hydrochlorothiazide)and irbesartan?
• Do not take HCTZ and irbesartan if you are pregnant or planning a pregnancy amiloride hctz. When used during the second and third trimesters of pregnancy, irbesartan cancause injury and even death to the developing baby amiloride hctz. Notify your doctor immediatelyif you think you might be pregnant amiloride hctz.
• Use caution when driving, operating machinery, or performing other hazardousactivities amiloride hctz. HCTZ (hydrochlorothiazide) and irbesartan may cause dizziness ordrowsiness amiloride hctz. If you experience dizziness or drowsiness, avoid these activities amiloride hctz. Also use caution when rising from a sitting or lying position amiloride hctz.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs amiloride hctz.
• Use alcohol cautiously amiloride hctz. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking an HCTZ and irbesartan amiloride hctz.
• Avoid prolonged exposure to sunlight amiloride hctz. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight amiloride hctz. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable amiloride hctz.
What are HCTZ and irbesartan?
• Irbesartan is an angiotensin II receptor inhibitor, also called angiotensinII receptor antagonist, and is used to treat hypertension (high blood pressure) amiloride hctz.
• HCTZ is a thiazide diuretic (water pill) amiloride hctz. It increases the amount ofwater and salt you lose in your urine and decreases edema (swelling or fluidretention) amiloride hctz.
• Together, HCTZ and irbesartan are used to reduce hypertension (high bloodpressure) amiloride hctz.
• HCTZ and irbesartan may also be used for purposes other than those listedin this medication guide amiloride hctz.
Who should not take HCTZ and irbesartan?
• Do not take HCTZ and irbesartan without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics amiloride hctz. You mayhave an allergic reaction to hydrochlorothiazide amiloride hctz.
• Before taking HCTZ and irbesartan, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have high levels of cholesterol or triglycerides in your blood;
· have high levels of potassium in your blood; or
· are taking potassium a supplement (e.g., K-Dur, Klor-Con, others),or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) amiloride hctz.
• You may not be able to take HCTZ and irbesartan, or you may require adosage adjustment or special monitoring during treatment if you have any ofthe conditions listed above amiloride hctz.
• HCTZ and irbesartan is in the FDA pregnancy category D amiloride hctz. This means thatit is known to cause birth defects in an unborn baby amiloride hctz. When used during the secondand third trimesters of pregnancy, irbesartan can cause injury and even deathof the developing baby amiloride hctz. Do not take this medication if you are pregnant amiloride hctz.
• HCTZ passes into breast milk and may harm a nursing infant amiloride hctz. It is notknown whether irbesartan passes into breast milk amiloride hctz. Do not take this medicationwithout first talking to your doctor if you are breast-feeding a baby amiloride hctz.
How should I take HCTZ and irbesartan?
• Take HCTZ and irbesartan exactly as directed by your doctor amiloride hctz. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you amiloride hctz.
• Take each dose with a full glass of water amiloride hctz.
• HCTZ and irbesartan can be taken with or without food amiloride hctz.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs amiloride hctz.
• Do not stop taking this medication without first talking to your doctor amiloride hctz. If you stop taking this medication suddenly, your condition could become worse amiloride hctz.
• Store HCTZ and irbesartan at room temperature away from moisture andheat amiloride hctz.
What happens if I miss a dose?
• Take the missed dose as soon as you remember amiloride hctz. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose amiloride hctz. Do not take a double dose of this medication amiloride hctz.
What happens if I overdose?
• Seek emergency medical attention amiloride hctz.
• Symptoms of an overdose of HCTZ and irbesartan are not well known butmay include dizziness, weakness, fainting, fatigue, low blood pressure, andchanges in heart rate amiloride hctz.
What should I avoid while taking HCTZ and irbesartan?
• Use caution when driving, operating machinery, or performing other hazardousactivities amiloride hctz. HCTZ and irbesartan may cause dizziness or drowsiness amiloride hctz. If you experiencedizziness or drowsiness, avoid these activities amiloride hctz. Also, use caution when risingfrom a sitting or lying position amiloride hctz.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs amiloride hctz.
• Use alcohol cautiously amiloride hctz. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking HCTZ and irbesartan amiloride hctz.
• Avoid a diet high in salt amiloride hctz. Too much salt may cause your body to retainwater amiloride hctz. Talk to your doctor before making changes in your diet amiloride hctz.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor amiloride hctz. HCTZ and irbesartan can affect potassium levels in yourbody amiloride hctz.
• Avoid prolonged exposure to sunlight amiloride hctz. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight amiloride hctz. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable amiloride hctz.
• Avoid becoming overheated in hot weather amiloride hctz. It is easy to become dangerouslydehydrated while you are taking HCTZ and irbesartan amiloride hctz.
What are the possible side effects of HCTZ and irbesartan?
• If you experience any of the following serious side effects, stop takingthis medication and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· fast heartbeats;
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion; or
· fainting amiloride hctz.
• Other, less serious side effects may be more likely to occur amiloride hctz. Continueto take the medication and talk to your doctor if you experience
· dizziness;
· nausea or upset stomach;
· diarrhea;
· headache;
· cough;
· muscle pain or cramps;
· rash; or
· anxiety or nervousness amiloride hctz.
• Side effects other than those listed here may also occur amiloride hctz. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome amiloride hctz.
What other drugs will affect HCTZ and irbesartan?
• Before taking HCTZ and irbesartan, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· a steroid medicine such as prednisone (Orasone, Deltasone, others),methylprednisolone (Medrol), prednisolone (Pediapred, Prelone), and others;
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) amiloride hctz.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above amiloride hctz.
• Drugs other than those listed here may also interact with HCTZ and irbesartanor affect your condition amiloride hctz. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines amiloride hctz.
Where can I get more information?
• Your pharmacist has additional information about HCTZ and irbesartanwritten for health professionals that you may read amiloride hctz.
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