hctz and pdr
(hyde droe klor oh THYE a zide and ER beh sar tan)
Avalide
What is the most important information I should know about HCTZ (hydrochlorothiazide)and irbesartan?
• Do not take HCTZ and irbesartan if you are pregnant or planning a pregnancy hctz and pdr. When used during the second and third trimesters of pregnancy, irbesartan cancause injury and even death to the developing baby hctz and pdr. Notify your doctor immediatelyif you think you might be pregnant hctz and pdr.
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz and pdr. HCTZ (hydrochlorothiazide) and irbesartan may cause dizziness ordrowsiness hctz and pdr. If you experience dizziness or drowsiness, avoid these activities hctz and pdr. Also use caution when rising from a sitting or lying position hctz and pdr.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz and pdr.
• Use alcohol cautiously hctz and pdr. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking an HCTZ and irbesartan hctz and pdr.
• Avoid prolonged exposure to sunlight hctz and pdr. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz and pdr. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz and pdr.
What are HCTZ and irbesartan?
• Irbesartan is an angiotensin II receptor inhibitor, also called angiotensinII receptor antagonist, and is used to treat hypertension (high blood pressure) hctz and pdr.
• HCTZ is a thiazide diuretic (water pill) hctz and pdr. It increases the amount ofwater and salt you lose in your urine and decreases edema (swelling or fluidretention) hctz and pdr.
• Together, HCTZ and irbesartan are used to reduce hypertension (high bloodpressure) hctz and pdr.
• HCTZ and irbesartan may also be used for purposes other than those listedin this medication guide hctz and pdr.
Who should not take HCTZ and irbesartan?
• Do not take HCTZ and irbesartan without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics hctz and pdr. You mayhave an allergic reaction to hydrochlorothiazide hctz and pdr.
• Before taking HCTZ and irbesartan, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have high levels of cholesterol or triglycerides in your blood;
· have high levels of potassium in your blood; or
· are taking potassium a supplement (e.g., K-Dur, Klor-Con, others),or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) hctz and pdr.
• You may not be able to take HCTZ and irbesartan, or you may require adosage adjustment or special monitoring during treatment if you have any ofthe conditions listed above hctz and pdr.
• HCTZ and irbesartan is in the FDA pregnancy category D hctz and pdr. This means thatit is known to cause birth defects in an unborn baby hctz and pdr. When used during the secondand third trimesters of pregnancy, irbesartan can cause injury and even deathof the developing baby hctz and pdr. Do not take this medication if you are pregnant hctz and pdr.
• HCTZ passes into breast milk and may harm a nursing infant hctz and pdr. It is notknown whether irbesartan passes into breast milk hctz and pdr. Do not take this medicationwithout first talking to your doctor if you are breast-feeding a baby hctz and pdr.
How should I take HCTZ and irbesartan?
• Take HCTZ and irbesartan exactly as directed by your doctor hctz and pdr. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you hctz and pdr.
• Take each dose with a full glass of water hctz and pdr.
• HCTZ and irbesartan can be taken with or without food hctz and pdr.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz and pdr.
• Do not stop taking this medication without first talking to your doctor hctz and pdr. If you stop taking this medication suddenly, your condition could become worse hctz and pdr.
• Store HCTZ and irbesartan at room temperature away from moisture andheat hctz and pdr.
What happens if I miss a dose?
• Take the missed dose as soon as you remember hctz and pdr. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose hctz and pdr. Do not take a double dose of this medication hctz and pdr.
What happens if I overdose?
• Seek emergency medical attention hctz and pdr.
• Symptoms of an overdose of HCTZ and irbesartan are not well known butmay include dizziness, weakness, fainting, fatigue, low blood pressure, andchanges in heart rate hctz and pdr.
What should I avoid while taking HCTZ and irbesartan?
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz and pdr. HCTZ and irbesartan may cause dizziness or drowsiness hctz and pdr. If you experiencedizziness or drowsiness, avoid these activities hctz and pdr. Also, use caution when risingfrom a sitting or lying position hctz and pdr.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz and pdr.
• Use alcohol cautiously hctz and pdr. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking HCTZ and irbesartan hctz and pdr.
• Avoid a diet high in salt hctz and pdr. Too much salt may cause your body to retainwater hctz and pdr. Talk to your doctor before making changes in your diet hctz and pdr.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor hctz and pdr. HCTZ and irbesartan can affect potassium levels in yourbody hctz and pdr.
• Avoid prolonged exposure to sunlight hctz and pdr. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz and pdr. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz and pdr.
• Avoid becoming overheated in hot weather hctz and pdr. It is easy to become dangerouslydehydrated while you are taking HCTZ and irbesartan hctz and pdr.
What are the possible side effects of HCTZ and irbesartan?
• If you experience any of the following serious side effects, stop takingthis medication and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· fast heartbeats;
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion; or
· fainting hctz and pdr.
• Other, less serious side effects may be more likely to occur hctz and pdr. Continueto take the medication and talk to your doctor if you experience
· dizziness;
· nausea or upset stomach;
· diarrhea;
· headache;
· cough;
· muscle pain or cramps;
· rash; or
· anxiety or nervousness hctz and pdr.
• Side effects other than those listed here may also occur hctz and pdr. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hctz and pdr.
What other drugs will affect HCTZ and irbesartan?
• Before taking HCTZ and irbesartan, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· a steroid medicine such as prednisone (Orasone, Deltasone, others),methylprednisolone (Medrol), prednisolone (Pediapred, Prelone), and others;
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) hctz and pdr.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above hctz and pdr.
• Drugs other than those listed here may also interact with HCTZ and irbesartanor affect your condition hctz and pdr. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines hctz and pdr.
Where can I get more information?
• Your pharmacist has additional information about HCTZ and irbesartanwritten for health professionals that you may read hctz and pdr.
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