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(hyde droe klor oh THYE a zide and ER beh sar tan)
Avalide
What is the most important information I should know about HCTZ (hydrochlorothiazide)and irbesartan?
• Do not take HCTZ and irbesartan if you are pregnant or planning a pregnancy hctz online. When used during the second and third trimesters of pregnancy, irbesartan cancause injury and even death to the developing baby hctz online. Notify your doctor immediatelyif you think you might be pregnant hctz online.
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz online. HCTZ (hydrochlorothiazide) and irbesartan may cause dizziness ordrowsiness hctz online. If you experience dizziness or drowsiness, avoid these activities hctz online. Also use caution when rising from a sitting or lying position hctz online.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz online.
• Use alcohol cautiously hctz online. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking an HCTZ and irbesartan hctz online.
• Avoid prolonged exposure to sunlight hctz online. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz online. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz online.
What are HCTZ and irbesartan?
• Irbesartan is an angiotensin II receptor inhibitor, also called angiotensinII receptor antagonist, and is used to treat hypertension (high blood pressure) hctz online.
• HCTZ is a thiazide diuretic (water pill) hctz online. It increases the amount ofwater and salt you lose in your urine and decreases edema (swelling or fluidretention) hctz online.
• Together, HCTZ and irbesartan are used to reduce hypertension (high bloodpressure) hctz online.
• HCTZ and irbesartan may also be used for purposes other than those listedin this medication guide hctz online.
Who should not take HCTZ and irbesartan?
• Do not take HCTZ and irbesartan without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics hctz online. You mayhave an allergic reaction to hydrochlorothiazide hctz online.
• Before taking HCTZ and irbesartan, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have high levels of cholesterol or triglycerides in your blood;
· have high levels of potassium in your blood; or
· are taking potassium a supplement (e.g., K-Dur, Klor-Con, others),or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) hctz online.
• You may not be able to take HCTZ and irbesartan, or you may require adosage adjustment or special monitoring during treatment if you have any ofthe conditions listed above hctz online.
• HCTZ and irbesartan is in the FDA pregnancy category D hctz online. This means thatit is known to cause birth defects in an unborn baby hctz online. When used during the secondand third trimesters of pregnancy, irbesartan can cause injury and even deathof the developing baby hctz online. Do not take this medication if you are pregnant hctz online.
• HCTZ passes into breast milk and may harm a nursing infant hctz online. It is notknown whether irbesartan passes into breast milk hctz online. Do not take this medicationwithout first talking to your doctor if you are breast-feeding a baby hctz online.
How should I take HCTZ and irbesartan?
• Take HCTZ and irbesartan exactly as directed by your doctor hctz online. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you hctz online.
• Take each dose with a full glass of water hctz online.
• HCTZ and irbesartan can be taken with or without food hctz online.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz online.
• Do not stop taking this medication without first talking to your doctor hctz online. If you stop taking this medication suddenly, your condition could become worse hctz online.
• Store HCTZ and irbesartan at room temperature away from moisture andheat hctz online.
What happens if I miss a dose?
• Take the missed dose as soon as you remember hctz online. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose hctz online. Do not take a double dose of this medication hctz online.
What happens if I overdose?
• Seek emergency medical attention hctz online.
• Symptoms of an overdose of HCTZ and irbesartan are not well known butmay include dizziness, weakness, fainting, fatigue, low blood pressure, andchanges in heart rate hctz online.
What should I avoid while taking HCTZ and irbesartan?
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz online. HCTZ and irbesartan may cause dizziness or drowsiness hctz online. If you experiencedizziness or drowsiness, avoid these activities hctz online. Also, use caution when risingfrom a sitting or lying position hctz online.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz online.
• Use alcohol cautiously hctz online. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking HCTZ and irbesartan hctz online.
• Avoid a diet high in salt hctz online. Too much salt may cause your body to retainwater hctz online. Talk to your doctor before making changes in your diet hctz online.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor hctz online. HCTZ and irbesartan can affect potassium levels in yourbody hctz online.
• Avoid prolonged exposure to sunlight hctz online. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz online. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz online.
• Avoid becoming overheated in hot weather hctz online. It is easy to become dangerouslydehydrated while you are taking HCTZ and irbesartan hctz online.
What are the possible side effects of HCTZ and irbesartan?
• If you experience any of the following serious side effects, stop takingthis medication and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· fast heartbeats;
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion; or
· fainting hctz online.
• Other, less serious side effects may be more likely to occur hctz online. Continueto take the medication and talk to your doctor if you experience
· dizziness;
· nausea or upset stomach;
· diarrhea;
· headache;
· cough;
· muscle pain or cramps;
· rash; or
· anxiety or nervousness hctz online.
• Side effects other than those listed here may also occur hctz online. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hctz online.
What other drugs will affect HCTZ and irbesartan?
• Before taking HCTZ and irbesartan, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· a steroid medicine such as prednisone (Orasone, Deltasone, others),methylprednisolone (Medrol), prednisolone (Pediapred, Prelone), and others;
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) hctz online.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above hctz online.
• Drugs other than those listed here may also interact with HCTZ and irbesartanor affect your condition hctz online. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines hctz online.
Where can I get more information?
• Your pharmacist has additional information about HCTZ and irbesartanwritten for health professionals that you may read hctz online.
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