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hctz water pill
(hyde droe klor oh THYE a zide and ER beh sar tan)
Avalide

What is the most important information I should know about HCTZ (hydrochlorothiazide)and irbesartan?
• Do not take HCTZ and irbesartan if you are pregnant or planning a pregnancy hctz water pill. When used during the second and third trimesters of pregnancy, irbesartan cancause injury and even death to the developing baby hctz water pill. Notify your doctor immediatelyif you think you might be pregnant hctz water pill.
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz water pill. HCTZ (hydrochlorothiazide) and irbesartan may cause dizziness ordrowsiness hctz water pill. If you experience dizziness or drowsiness, avoid these activities hctz water pill. Also use caution when rising from a sitting or lying position hctz water pill.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz water pill.
• Use alcohol cautiously hctz water pill. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking an HCTZ and irbesartan hctz water pill.
• Avoid prolonged exposure to sunlight hctz water pill. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz water pill. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz water pill.


What are HCTZ and irbesartan?
• Irbesartan is an angiotensin II receptor inhibitor, also called angiotensinII receptor antagonist, and is used to treat hypertension (high blood pressure) hctz water pill.
• HCTZ is a thiazide diuretic (water pill) hctz water pill. It increases the amount ofwater and salt you lose in your urine and decreases edema (swelling or fluidretention) hctz water pill.
• Together, HCTZ and irbesartan are used to reduce hypertension (high bloodpressure) hctz water pill.
• HCTZ and irbesartan may also be used for purposes other than those listedin this medication guide hctz water pill.


Who should not take HCTZ and irbesartan?
• Do not take HCTZ and irbesartan without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics hctz water pill. You mayhave an allergic reaction to hydrochlorothiazide hctz water pill.
• Before taking HCTZ and irbesartan, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have high levels of cholesterol or triglycerides in your blood;
· have high levels of potassium in your blood; or
· are taking potassium a supplement (e.g., K-Dur, Klor-Con, others),or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) hctz water pill.
• You may not be able to take HCTZ and irbesartan, or you may require adosage adjustment or special monitoring during treatment if you have any ofthe conditions listed above hctz water pill.
• HCTZ and irbesartan is in the FDA pregnancy category D hctz water pill. This means thatit is known to cause birth defects in an unborn baby hctz water pill. When used during the secondand third trimesters of pregnancy, irbesartan can cause injury and even deathof the developing baby hctz water pill. Do not take this medication if you are pregnant hctz water pill.
• HCTZ passes into breast milk and may harm a nursing infant hctz water pill. It is notknown whether irbesartan passes into breast milk hctz water pill. Do not take this medicationwithout first talking to your doctor if you are breast-feeding a baby hctz water pill.


How should I take HCTZ and irbesartan?
• Take HCTZ and irbesartan exactly as directed by your doctor hctz water pill. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you hctz water pill.
• Take each dose with a full glass of water hctz water pill.
• HCTZ and irbesartan can be taken with or without food hctz water pill.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz water pill.
• Do not stop taking this medication without first talking to your doctor hctz water pill. If you stop taking this medication suddenly, your condition could become worse hctz water pill.
• Store HCTZ and irbesartan at room temperature away from moisture andheat hctz water pill.


What happens if I miss a dose?
• Take the missed dose as soon as you remember hctz water pill. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose hctz water pill. Do not take a double dose of this medication hctz water pill.


What happens if I overdose?
• Seek emergency medical attention hctz water pill.
• Symptoms of an overdose of HCTZ and irbesartan are not well known butmay include dizziness, weakness, fainting, fatigue, low blood pressure, andchanges in heart rate hctz water pill.


What should I avoid while taking HCTZ and irbesartan?
• Use caution when driving, operating machinery, or performing other hazardousactivities hctz water pill. HCTZ and irbesartan may cause dizziness or drowsiness hctz water pill. If you experiencedizziness or drowsiness, avoid these activities hctz water pill. Also, use caution when risingfrom a sitting or lying position hctz water pill.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs hctz water pill.
• Use alcohol cautiously hctz water pill. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking HCTZ and irbesartan hctz water pill.
• Avoid a diet high in salt hctz water pill. Too much salt may cause your body to retainwater hctz water pill. Talk to your doctor before making changes in your diet hctz water pill.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor hctz water pill. HCTZ and irbesartan can affect potassium levels in yourbody hctz water pill.
• Avoid prolonged exposure to sunlight hctz water pill. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight hctz water pill. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hctz water pill.
• Avoid becoming overheated in hot weather hctz water pill. It is easy to become dangerouslydehydrated while you are taking HCTZ and irbesartan hctz water pill.


What are the possible side effects of HCTZ and irbesartan?
• If you experience any of the following serious side effects, stop takingthis medication and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· fast heartbeats;
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion; or
· fainting hctz water pill.
• Other, less serious side effects may be more likely to occur hctz water pill. Continueto take the medication and talk to your doctor if you experience
· dizziness;
· nausea or upset stomach;
· diarrhea;
· headache;
· cough;
· muscle pain or cramps;
· rash; or
· anxiety or nervousness hctz water pill.
• Side effects other than those listed here may also occur hctz water pill. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hctz water pill.


What other drugs will affect HCTZ and irbesartan?
• Before taking HCTZ and irbesartan, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· a steroid medicine such as prednisone (Orasone, Deltasone, others),methylprednisolone (Medrol), prednisolone (Pediapred, Prelone), and others;
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) hctz water pill.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above hctz water pill.
• Drugs other than those listed here may also interact with HCTZ and irbesartanor affect your condition hctz water pill. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines hctz water pill.


Where can I get more information?
• Your pharmacist has additional information about HCTZ and irbesartanwritten for health professionals that you may read hctz water pill.


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