trimeter hctz edema
(hyde droe klor oh THYE a zide and ER beh sar tan)
Avalide
What is the most important information I should know about HCTZ (hydrochlorothiazide)and irbesartan?
• Do not take HCTZ and irbesartan if you are pregnant or planning a pregnancy trimeter hctz edema. When used during the second and third trimesters of pregnancy, irbesartan cancause injury and even death to the developing baby trimeter hctz edema. Notify your doctor immediatelyif you think you might be pregnant trimeter hctz edema.
• Use caution when driving, operating machinery, or performing other hazardousactivities trimeter hctz edema. HCTZ (hydrochlorothiazide) and irbesartan may cause dizziness ordrowsiness trimeter hctz edema. If you experience dizziness or drowsiness, avoid these activities trimeter hctz edema. Also use caution when rising from a sitting or lying position trimeter hctz edema.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs trimeter hctz edema.
• Use alcohol cautiously trimeter hctz edema. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking an HCTZ and irbesartan trimeter hctz edema.
• Avoid prolonged exposure to sunlight trimeter hctz edema. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight trimeter hctz edema. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable trimeter hctz edema.
What are HCTZ and irbesartan?
• Irbesartan is an angiotensin II receptor inhibitor, also called angiotensinII receptor antagonist, and is used to treat hypertension (high blood pressure) trimeter hctz edema.
• HCTZ is a thiazide diuretic (water pill) trimeter hctz edema. It increases the amount ofwater and salt you lose in your urine and decreases edema (swelling or fluidretention) trimeter hctz edema.
• Together, HCTZ and irbesartan are used to reduce hypertension (high bloodpressure) trimeter hctz edema.
• HCTZ and irbesartan may also be used for purposes other than those listedin this medication guide trimeter hctz edema.
Who should not take HCTZ and irbesartan?
• Do not take HCTZ and irbesartan without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics trimeter hctz edema. You mayhave an allergic reaction to hydrochlorothiazide trimeter hctz edema.
• Before taking HCTZ and irbesartan, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have high levels of cholesterol or triglycerides in your blood;
· have high levels of potassium in your blood; or
· are taking potassium a supplement (e.g., K-Dur, Klor-Con, others),or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) trimeter hctz edema.
• You may not be able to take HCTZ and irbesartan, or you may require adosage adjustment or special monitoring during treatment if you have any ofthe conditions listed above trimeter hctz edema.
• HCTZ and irbesartan is in the FDA pregnancy category D trimeter hctz edema. This means thatit is known to cause birth defects in an unborn baby trimeter hctz edema. When used during the secondand third trimesters of pregnancy, irbesartan can cause injury and even deathof the developing baby trimeter hctz edema. Do not take this medication if you are pregnant trimeter hctz edema.
• HCTZ passes into breast milk and may harm a nursing infant trimeter hctz edema. It is notknown whether irbesartan passes into breast milk trimeter hctz edema. Do not take this medicationwithout first talking to your doctor if you are breast-feeding a baby trimeter hctz edema.
How should I take HCTZ and irbesartan?
• Take HCTZ and irbesartan exactly as directed by your doctor trimeter hctz edema. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you trimeter hctz edema.
• Take each dose with a full glass of water trimeter hctz edema.
• HCTZ and irbesartan can be taken with or without food trimeter hctz edema.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs trimeter hctz edema.
• Do not stop taking this medication without first talking to your doctor trimeter hctz edema. If you stop taking this medication suddenly, your condition could become worse trimeter hctz edema.
• Store HCTZ and irbesartan at room temperature away from moisture andheat trimeter hctz edema.
What happens if I miss a dose?
• Take the missed dose as soon as you remember trimeter hctz edema. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose trimeter hctz edema. Do not take a double dose of this medication trimeter hctz edema.
What happens if I overdose?
• Seek emergency medical attention trimeter hctz edema.
• Symptoms of an overdose of HCTZ and irbesartan are not well known butmay include dizziness, weakness, fainting, fatigue, low blood pressure, andchanges in heart rate trimeter hctz edema.
What should I avoid while taking HCTZ and irbesartan?
• Use caution when driving, operating machinery, or performing other hazardousactivities trimeter hctz edema. HCTZ and irbesartan may cause dizziness or drowsiness trimeter hctz edema. If you experiencedizziness or drowsiness, avoid these activities trimeter hctz edema. Also, use caution when risingfrom a sitting or lying position trimeter hctz edema.
• Stop taking HCTZ and irbesartan and contact your doctor if lightheadednessor fainting occurs trimeter hctz edema.
• Use alcohol cautiously trimeter hctz edema. Alcohol may increase the drowsiness and dizzinessthat may occur while you are taking HCTZ and irbesartan trimeter hctz edema.
• Avoid a diet high in salt trimeter hctz edema. Too much salt may cause your body to retainwater trimeter hctz edema. Talk to your doctor before making changes in your diet trimeter hctz edema.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor trimeter hctz edema. HCTZ and irbesartan can affect potassium levels in yourbody trimeter hctz edema.
• Avoid prolonged exposure to sunlight trimeter hctz edema. HCTZ and irbesartan may increasethe sensitivity of your skin to sunlight trimeter hctz edema. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable trimeter hctz edema.
• Avoid becoming overheated in hot weather trimeter hctz edema. It is easy to become dangerouslydehydrated while you are taking HCTZ and irbesartan trimeter hctz edema.
What are the possible side effects of HCTZ and irbesartan?
• If you experience any of the following serious side effects, stop takingthis medication and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· fast heartbeats;
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion; or
· fainting trimeter hctz edema.
• Other, less serious side effects may be more likely to occur trimeter hctz edema. Continueto take the medication and talk to your doctor if you experience
· dizziness;
· nausea or upset stomach;
· diarrhea;
· headache;
· cough;
· muscle pain or cramps;
· rash; or
· anxiety or nervousness trimeter hctz edema.
• Side effects other than those listed here may also occur trimeter hctz edema. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome trimeter hctz edema.
What other drugs will affect HCTZ and irbesartan?
• Before taking HCTZ and irbesartan, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· a steroid medicine such as prednisone (Orasone, Deltasone, others),methylprednisolone (Medrol), prednisolone (Pediapred, Prelone), and others;
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) trimeter hctz edema.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above trimeter hctz edema.
• Drugs other than those listed here may also interact with HCTZ and irbesartanor affect your condition trimeter hctz edema. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines trimeter hctz edema.
Where can I get more information?
• Your pharmacist has additional information about HCTZ and irbesartanwritten for health professionals that you may read trimeter hctz edema.
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