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recombinant humulin
insulin isophane and insulin regular (IN suh lin EYE sew fane and IN suh lin REHgue ler)

What is the most important information I should know about Humulin 70/30?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude shaking; nausea; headache; drowsiness; weakness; dizziness; fast heartbeat;sweating; pale, cool skin; anxiety; and difficulty concentrating recombinant humulin. Carry a pieceof candy or glucose tablets with you to treat episodes of low blood sugar recombinant humulin.
• Follow any diet and exercise plan that you have developed with your doctoror nurse recombinant humulin. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control your blood sugar levels recombinant humulin.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever recombinant humulin. These illnesses may change your insulin requirements recombinant humulin.
• Do not change the brand of insulin isophane and insulin regular or syringethat you are using without first talking to your doctor or pharmacist recombinant humulin. Somebrands of insulin isophane and insulin regular and syringes are interchangeable,while others are not recombinant humulin. Your doctor and/or pharmacist know which brands can besubstituted for one another recombinant humulin.


What is Humulin 70/30?
• Insulin is a hormone naturally produced by your pancreas recombinant humulin. Insulin enablesthe body to use the sugar in food as a source of energy recombinant humulin. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus recombinant humulin. This conditionallows sugar levels in the blood to become very high recombinant humulin. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels recombinant humulin.
• Humulin 70/30 is used in the treatment of diabetes mellitus recombinant humulin.
• Humulin 70/30 may also be used for purposes other than those listed inthis medication guide recombinant humulin.


What should I discuss with my healthcare provider before using Humulin 70/30?
• Do not use Humulin 70/30 if you are allergic to insulin or if you haveintolerance to a certain insulin isophane and insulin regular product recombinant humulin.
• Before using insulin, tell your doctor if you have any other medicalconditions or if you take other prescription or over-the-counter medications,including vitamins, minerals, and herbal supplements recombinant humulin.
• Before using Humulin 70/30, tell your doctor if you have kidney or liverdisease recombinant humulin. You may require a dosage adjustment or special monitoring during treatment recombinant humulin.
• Most insulins can be used during pregnancy and breast-feeding recombinant humulin. They arenot expected to be harmful to an unborn baby recombinant humulin. It is very important to controlblood sugar levels during pregnancy and breast-feeding and insulin is oftenchosen as the treatment recombinant humulin. Some types of insulin may be better than others foruse during pregnancy and breast-feeding recombinant humulin. Talk to your doctor about the use ofinsulin during pregnancy and breast-feeding recombinant humulin.


How should I use Humulin 70/30?
• Use Humulin 70/30 exactly as directed by your doctor recombinant humulin. If you do not understandthese instructions, ask your doctor, nurse, or pharmacist to explain them toyou recombinant humulin.
• If the insulin has been stored in the refrigerator, it can be warmedto room temperature before use recombinant humulin.
• Roll the container of insulin between your palms 10 times recombinant humulin. Then, if youare using a pen or prefilled syringe, turn it upside down so that the glassball moves from one end to the other recombinant humulin. Do this at least 10 times recombinant humulin. Repeat thisprocedure until the suspension appears uniformly white and cloudy recombinant humulin. Do not shakethe insulin vigorously recombinant humulin. Inject immediately recombinant humulin. Repeat this procedure before eachsubsequent injection recombinant humulin.
• Do not use the insulin if it is discolored, has particles in it, or looksdifferent from previous vials, cartridges, or prefilled syringes of Humulin70/30 recombinant humulin.
• Use only the approved delivery device(s) for cartridges or prefilledsyringes of insulin recombinant humulin.
• If you are mixing different types of insulins in the same syringe, followyour doctor's directions and always draw up the different insulins in the sameorder (usually the clear insulin first) recombinant humulin. Do not mix different insulins in thesame syringe unless specifically directed to do so by your doctor recombinant humulin.
• Rotate injection sites exactly as directed by your doctor recombinant humulin. Usually, youshould not inject within 1 inch of the same site within 1 month recombinant humulin.
• Never reuse a needle or syringe recombinant humulin. Dispose of all needles and syringesin an appropriate, puncture-resistant disposal container recombinant humulin.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,50/50 isophane-regular mixture, 70/30 isophane-regular mixture, etc.) unlessyour doctor recommends a change for you recombinant humulin.
• Do not change the brand of insulin isophane and insulin regular or syringethat you are using without first talking to your doctor or pharmacist recombinant humulin. Somebrands of insulin isophane and insulin regular and syringes are interchangeable,while others are not recombinant humulin.
• Follow any diet and exercise plan that you have developed with your doctoror nurse recombinant humulin. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control your blood sugar levels recombinant humulin.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever recombinant humulin. These illnesses may change your insulin requirements recombinant humulin.
• Your healthcare provider may recommend regular monitoring of blood sugarlevels with blood or urine tests recombinant humulin.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency recombinant humulin.
• Proper foot care, eye care, dental care, and overall proper health careare important for people with diabetes recombinant humulin. Visit your doctor, dentist, eye doctor,and other heath care practitioners as recommended by your doctor recombinant humulin.
• Store unopened vials, pens, and cartridges of Humulin 70/30 in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius), in the originalcarton recombinant humulin. Do not store Humulin 70/30 in the freezer and do not allow it to freeze recombinant humulin. Do not use Humulin 70/30 if it has been frozen recombinant humulin. Throw away any expired insulin recombinant humulin.
• Vials of Humulin 70/30 can be kept unrefrigerated for up to 28 days,but should not be exposed to excessive heat or sunlight recombinant humulin.
• Once punctured, the vial of insulin in use, whether stored in the refrigeratoror at room temperature, must be used within 28 days recombinant humulin. Throw away any unused insulin28 days after the vial is first punctured recombinant humulin.
• Insulin cartridges and pens in use, should be stored at room temperature(below 86 degrees Fahrenheit/30 degrees Celsius), but should not be exposedto excessive heat or sunlight recombinant humulin. Novolin 70/30 PenFill and Prefilled cartridgesand Humulin 70/30 cartridges in use can be kept unrefrigerated for one week recombinant humulin. Humulin 70/30 Pens and Novolin 70/30 Innolets in use can be kept unrefrigeratedfor 10 days recombinant humulin. Unrefrigerated cartridges, pens, and Innolets must be used withinthis time period or discarded recombinant humulin.


What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin recombinant humulin. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation recombinant humulin.


What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected recombinant humulin.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety recombinant humulin.


What should I avoid while using Humulin 70/30?
• Do not use alcohol without first talking to your doctor recombinant humulin. It lowers bloodsugar, and you may experience dangerously low blood sugar levels recombinant humulin.


What are the possible side effects of Humulin 70/30?
• Rarely, people have allergic reactions to insulin recombinant humulin. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof the throat; swelling of the lips, tongue, or face; or hives) recombinant humulin.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low recombinant humulin. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions recombinant humulin. Also, be sure your family and close friends know how to help you in an emergency recombinant humulin.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations recombinant humulin.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking;nausea; headache; drowsiness; weakness; dizziness; fast heartbeat; sweating;pale, cool skin; anxiety; and difficulty concentrating recombinant humulin.
• Keep sugary candy, fruit juice, or glucose tablets on hand to treat episodesof low blood sugar recombinant humulin.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food than usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations recombinant humulin.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination recombinant humulin.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high recombinant humulin.
• Side effects may also occur at the site of injection recombinant humulin. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain recombinant humulin.
• Side effects other than those listed here may also occur recombinant humulin. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome recombinant humulin.


What other drugs will affect Humulin 70/30?
• Many drugs can interact with insulin or affect blood sugar levels recombinant humulin. Donot take any other prescription or over-the-counter medicines, including vitamins,minerals, and herbal products, without first talking to your doctor or pharmacistduring treatment with insulin recombinant humulin.


Where can I get more information?
• Your pharmacist has additional information about Humulin 70/30 writtenfor health professionals that you may read recombinant humulin.


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