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What is the most important information I should know about hydrochlorothiazide?
• To reduce nighttime urination, take hydrochlorothiazide early in theday unless otherwise directed by your doctor hydrochlorothiazide 25 mg description picture.
• Use caution when driving, operating machinery, or performing other hazardousactivities hydrochlorothiazide 25 mg description picture. Hydrochlorothiazide may cause dizziness hydrochlorothiazide 25 mg description picture. If you experience dizziness,avoid these activities hydrochlorothiazide 25 mg description picture.


What is hydrochlorothiazide?
• Hydrochlorothiazide is a thiazide diuretic (water pill) hydrochlorothiazide 25 mg description picture. It decreasesthe amount of fluid in your body by increasing the amount of salt and wateryou lose in your urine hydrochlorothiazide 25 mg description picture.
• Hydrochlorothiazide is used to lower blood pressure and to decrease edema(swelling) hydrochlorothiazide 25 mg description picture.
• Hydrochlorothiazide may also be used for purposes other than those listedin this medication guide hydrochlorothiazide 25 mg description picture.


Who should not take hydrochlorothiazide?
• Do not take hydrochlorothiazide without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics hydrochlorothiazide 25 mg description picture. You mayhave an allergic reaction to hydrochlorothiazide hydrochlorothiazide 25 mg description picture.
• Before taking hydrochlorothiazide, tell your doctor if you have
· diabetes,
· gout,
· a collagen vascular disease such as systemic lupus erythematosus,
· pancreatitis,
· kidney disease,
· liver disease, or
· high levels of cholesterol or triglycerides (types of fat) in yourblood hydrochlorothiazide 25 mg description picture.
• You may need a dosage adjustment or special monitoring during therapyif you have any of the conditions listed above hydrochlorothiazide 25 mg description picture.
• Hydrochlorothiazide is in the FDA pregnancy category B hydrochlorothiazide 25 mg description picture. This means thatit is not expected to harm an unborn baby hydrochlorothiazide 25 mg description picture. Do not take hydrochlorothiazide withoutfirst talking to your doctor if you are pregnant hydrochlorothiazide 25 mg description picture.
• Hydrochlorothiazide passes into breast milk and may harm a nursing infant hydrochlorothiazide 25 mg description picture. Do not take hydrochlorothiazide without first talking to your doctor if youare breast-feeding a baby hydrochlorothiazide 25 mg description picture.


How should I take hydrochlorothiazide?
• Take hydrochlorothiazide exactly as directed by your doctor hydrochlorothiazide 25 mg description picture. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you hydrochlorothiazide 25 mg description picture.
• Take each dose with a full glass of water hydrochlorothiazide 25 mg description picture.
• To reduce nighttime urination, take hydrochlorothiazide early in theday unless otherwise directed by your doctor hydrochlorothiazide 25 mg description picture.
• Do not stop taking hydrochlorothiazide suddenly even if you feel better hydrochlorothiazide 25 mg description picture. Stopping suddenly could make your condition worse hydrochlorothiazide 25 mg description picture.
• Store this medication at room temperature away from moisture and heat hydrochlorothiazide 25 mg description picture.


What happens if I miss a dose?
• Take the missed dose as soon as you remember hydrochlorothiazide 25 mg description picture. However, if it is almosttime for your next dose, skip the dose you missed and take only your next regularlyscheduled dose hydrochlorothiazide 25 mg description picture. Do not take a double dose of this medication hydrochlorothiazide 25 mg description picture.


What happens if I overdose?
• Seek emergency medical attention hydrochlorothiazide 25 mg description picture.
• Symptoms of a hydrochlorothiazide overdose include increased urination,nausea, vomiting, diarrhea, fatigue, lethargy, and unconsciousness hydrochlorothiazide 25 mg description picture.


What should I avoid while taking hydrochlorothiazide?
• Use caution when driving, operating machinery, or performing other hazardousactivities hydrochlorothiazide 25 mg description picture. Hydrochlorothiazide may cause dizziness hydrochlorothiazide 25 mg description picture. If you experience dizziness,avoid these activities hydrochlorothiazide 25 mg description picture.
• Use alcohol cautiously hydrochlorothiazide 25 mg description picture. Alcohol may increase the side effects of hydrochlorothiazide hydrochlorothiazide 25 mg description picture.
• Avoid a diet high in salt hydrochlorothiazide 25 mg description picture. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide hydrochlorothiazide 25 mg description picture.
• Avoid prolonged exposure to sunlight hydrochlorothiazide 25 mg description picture. Hydrochlorothiazide may increasethe sensitivity of your skin to sunlight hydrochlorothiazide 25 mg description picture. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable hydrochlorothiazide 25 mg description picture.
• Avoid becoming overheated in hot weather and during exercise hydrochlorothiazide 25 mg description picture. It is easierto become dangerously dehydrated while taking hydrochlorothiazide hydrochlorothiazide 25 mg description picture.


What are the possible side effects of hydrochlorothiazide?
• If you experience any of the following serious side effects, stop takinghydrochlorothiazide and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· unusual fatigue;
· abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion;
· irregular heartbeats or a fluttering feeling in your chest; or
· little or no urine hydrochlorothiazide 25 mg description picture.
• Other, less serious side effects are more likely to occur hydrochlorothiazide 25 mg description picture. Continue totake hydrochlorothiazide and talk to your doctor if you experience
· dizziness, especially when you switch to sitting or standing from alying position;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite;
· abdominal pain;
· sensitivity to sunlight; or
· impotence hydrochlorothiazide 25 mg description picture.
• Side effects other than those listed here may also occur hydrochlorothiazide 25 mg description picture. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hydrochlorothiazide 25 mg description picture.


What other drugs will affect hydrochlorothiazide?
• Before taking hydrochlorothiazide tell your doctor if you are takingany of the following medications:
· lithium (Lithobid, Eskalith, others);
· digoxin (Lanoxin, Lanoxicaps);
· the cholesterol-lowering drugs cholestyramine (Questran) or colestipol(Colestid);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, OrudisKT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac(Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac(Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), orflurbiprofen (Ansaid);
· a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase,Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide(Orinase), and others; or
· a steroid medicine such as cortisone (Cortone), dexamethasone (Decadron,Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone),prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others hydrochlorothiazide 25 mg description picture.
• You may not be able to take hydrochlorothiazide, or you may require adosage adjustment or special monitoring during treatment if you are taking anyof the medications listed above hydrochlorothiazide 25 mg description picture.
• Also, before taking hydrochlorothiazide, tell your doctor if you aretaking any other medicine to treat high blood pressure, water retention, heartproblems, prostate problems, or another condition hydrochlorothiazide 25 mg description picture. Some medicines used to treatthese conditions may interact with hydrochlorothiazide and the effects on yourheart may be increased hydrochlorothiazide 25 mg description picture.
• Hydrochlorothiazide may increase the effects of other drugs that causedrowsiness, including sedatives (used to treat insomnia), pain relievers, seizuremedicines, antidepressants, alcohol, antihistamines, anxiety medicines, andmuscle relaxants hydrochlorothiazide 25 mg description picture. Tell your doctor about all medicines that you are taking,and do not take any medicine without first talking to your doctor hydrochlorothiazide 25 mg description picture.
• Drugs other than those listed here may also interact with hydrochlorothiazideor affect your condition hydrochlorothiazide 25 mg description picture. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines hydrochlorothiazide 25 mg description picture.


Where can I get more information?
• Your pharmacist has additional information about hydrochlorothiazidewritten for health professionals that you may read hydrochlorothiazide 25 mg description picture.


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