olmesartan medoxomil hydrochlorothiazide

What is the most important information I should know about hydrochlorothiazide?
• To reduce nighttime urination, take hydrochlorothiazide early in theday unless otherwise directed by your doctor olmesartan medoxomil hydrochlorothiazide.
• Use caution when driving, operating machinery, or performing other hazardousactivities olmesartan medoxomil hydrochlorothiazide. Hydrochlorothiazide may cause dizziness olmesartan medoxomil hydrochlorothiazide. If you experience dizziness,avoid these activities olmesartan medoxomil hydrochlorothiazide.

What is hydrochlorothiazide?
• Hydrochlorothiazide is a thiazide diuretic (water pill) olmesartan medoxomil hydrochlorothiazide. It decreasesthe amount of fluid in your body by increasing the amount of salt and wateryou lose in your urine olmesartan medoxomil hydrochlorothiazide.
• Hydrochlorothiazide is used to lower blood pressure and to decrease edema(swelling) olmesartan medoxomil hydrochlorothiazide.
• Hydrochlorothiazide may also be used for purposes other than those listedin this medication guide olmesartan medoxomil hydrochlorothiazide.

Who should not take hydrochlorothiazide?
• Do not take hydrochlorothiazide without first talking to your doctorif you have an allergy to sulfa-based drugs such as sulfa antibiotics olmesartan medoxomil hydrochlorothiazide. You mayhave an allergic reaction to hydrochlorothiazide olmesartan medoxomil hydrochlorothiazide.
• Before taking hydrochlorothiazide, tell your doctor if you have
· diabetes,
· gout,
· a collagen vascular disease such as systemic lupus erythematosus,
· pancreatitis,
· kidney disease,
· liver disease, or
· high levels of cholesterol or triglycerides (types of fat) in yourblood olmesartan medoxomil hydrochlorothiazide.
• You may need a dosage adjustment or special monitoring during therapyif you have any of the conditions listed above olmesartan medoxomil hydrochlorothiazide.
• Hydrochlorothiazide is in the FDA pregnancy category B olmesartan medoxomil hydrochlorothiazide. This means thatit is not expected to harm an unborn baby olmesartan medoxomil hydrochlorothiazide. Do not take hydrochlorothiazide withoutfirst talking to your doctor if you are pregnant olmesartan medoxomil hydrochlorothiazide.
• Hydrochlorothiazide passes into breast milk and may harm a nursing infant olmesartan medoxomil hydrochlorothiazide. Do not take hydrochlorothiazide without first talking to your doctor if youare breast-feeding a baby olmesartan medoxomil hydrochlorothiazide.

How should I take hydrochlorothiazide?
• Take hydrochlorothiazide exactly as directed by your doctor olmesartan medoxomil hydrochlorothiazide. If you donot understand these directions, ask your pharmacist, nurse, or doctor to explainthem to you olmesartan medoxomil hydrochlorothiazide.
• Take each dose with a full glass of water olmesartan medoxomil hydrochlorothiazide.
• To reduce nighttime urination, take hydrochlorothiazide early in theday unless otherwise directed by your doctor olmesartan medoxomil hydrochlorothiazide.
• Do not stop taking hydrochlorothiazide suddenly even if you feel better olmesartan medoxomil hydrochlorothiazide. Stopping suddenly could make your condition worse olmesartan medoxomil hydrochlorothiazide.
• Store this medication at room temperature away from moisture and heat olmesartan medoxomil hydrochlorothiazide.

What happens if I miss a dose?
• Take the missed dose as soon as you remember olmesartan medoxomil hydrochlorothiazide. However, if it is almosttime for your next dose, skip the dose you missed and take only your next regularlyscheduled dose olmesartan medoxomil hydrochlorothiazide. Do not take a double dose of this medication olmesartan medoxomil hydrochlorothiazide.

What happens if I overdose?
• Seek emergency medical attention olmesartan medoxomil hydrochlorothiazide.
• Symptoms of a hydrochlorothiazide overdose include increased urination,nausea, vomiting, diarrhea, fatigue, lethargy, and unconsciousness olmesartan medoxomil hydrochlorothiazide.

What should I avoid while taking hydrochlorothiazide?
• Use caution when driving, operating machinery, or performing other hazardousactivities olmesartan medoxomil hydrochlorothiazide. Hydrochlorothiazide may cause dizziness olmesartan medoxomil hydrochlorothiazide. If you experience dizziness,avoid these activities olmesartan medoxomil hydrochlorothiazide.
• Use alcohol cautiously olmesartan medoxomil hydrochlorothiazide. Alcohol may increase the side effects of hydrochlorothiazide olmesartan medoxomil hydrochlorothiazide.
• Avoid a diet high in salt olmesartan medoxomil hydrochlorothiazide. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide olmesartan medoxomil hydrochlorothiazide.
• Avoid prolonged exposure to sunlight olmesartan medoxomil hydrochlorothiazide. Hydrochlorothiazide may increasethe sensitivity of your skin to sunlight olmesartan medoxomil hydrochlorothiazide. Use a sunscreen and wear protectiveclothing when exposure to the sun is unavoidable olmesartan medoxomil hydrochlorothiazide.
• Avoid becoming overheated in hot weather and during exercise olmesartan medoxomil hydrochlorothiazide. It is easierto become dangerously dehydrated while taking hydrochlorothiazide olmesartan medoxomil hydrochlorothiazide.

What are the possible side effects of hydrochlorothiazide?
• If you experience any of the following serious side effects, stop takinghydrochlorothiazide and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· unusual fatigue;
· abnormal bleeding or bruising;
· yellow skin or eyes;
· confusion;
· irregular heartbeats or a fluttering feeling in your chest; or
· little or no urine olmesartan medoxomil hydrochlorothiazide.
• Other, less serious side effects are more likely to occur olmesartan medoxomil hydrochlorothiazide. Continue totake hydrochlorothiazide and talk to your doctor if you experience
· dizziness, especially when you switch to sitting or standing from alying position;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite;
· abdominal pain;
· sensitivity to sunlight; or
· impotence olmesartan medoxomil hydrochlorothiazide.
• Side effects other than those listed here may also occur olmesartan medoxomil hydrochlorothiazide. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome olmesartan medoxomil hydrochlorothiazide.

What other drugs will affect hydrochlorothiazide?
• Before taking hydrochlorothiazide tell your doctor if you are takingany of the following medications:
· lithium (Lithobid, Eskalith, others);
· digoxin (Lanoxin, Lanoxicaps);
· the cholesterol-lowering drugs cholestyramine (Questran) or colestipol(Colestid);
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, OrudisKT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac(Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac(Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), orflurbiprofen (Ansaid);
· a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase,Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide(Orinase), and others; or
· a steroid medicine such as cortisone (Cortone), dexamethasone (Decadron,Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone),prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others olmesartan medoxomil hydrochlorothiazide.
• You may not be able to take hydrochlorothiazide, or you may require adosage adjustment or special monitoring during treatment if you are taking anyof the medications listed above olmesartan medoxomil hydrochlorothiazide.
• Also, before taking hydrochlorothiazide, tell your doctor if you aretaking any other medicine to treat high blood pressure, water retention, heartproblems, prostate problems, or another condition olmesartan medoxomil hydrochlorothiazide. Some medicines used to treatthese conditions may interact with hydrochlorothiazide and the effects on yourheart may be increased olmesartan medoxomil hydrochlorothiazide.
• Hydrochlorothiazide may increase the effects of other drugs that causedrowsiness, including sedatives (used to treat insomnia), pain relievers, seizuremedicines, antidepressants, alcohol, antihistamines, anxiety medicines, andmuscle relaxants olmesartan medoxomil hydrochlorothiazide. Tell your doctor about all medicines that you are taking,and do not take any medicine without first talking to your doctor olmesartan medoxomil hydrochlorothiazide.
• Drugs other than those listed here may also interact with hydrochlorothiazideor affect your condition olmesartan medoxomil hydrochlorothiazide. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines olmesartan medoxomil hydrochlorothiazide.

Where can I get more information?
• Your pharmacist has additional information about hydrochlorothiazidewritten for health professionals that you may read olmesartan medoxomil hydrochlorothiazide.

Copyright 2005 D-S LTD.
All Rights Reserved.