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losartan and hydrochlorothiazide (low SAR tan and hye droe klor oh THYE a zide)

What is the most important information I should know about Hyzaar?
• Do not take Hyzaar if you are pregnant or planning a pregnancy canadian prescriptions hyzaar. Whenused during the second and third trimesters of pregnancy, losartan can causeinjury and even death to the developing fetus canadian prescriptions hyzaar. Notify your doctor immediatelyif you think you might be pregnant canadian prescriptions hyzaar.
• Use caution when driving, operating machinery, or performing other hazardousactivities canadian prescriptions hyzaar. Hyzaar may cause dizziness or drowsiness canadian prescriptions hyzaar. If you experience dizzinessor drowsiness, avoid these activities canadian prescriptions hyzaar. Also use caution when rising from a sittingor lying position canadian prescriptions hyzaar.
• Use alcohol cautiously canadian prescriptions hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar canadian prescriptions hyzaar.


What is Hyzaar?
• Losartan is in a class of drugs called angiotensin II receptor antagonists canadian prescriptions hyzaar.
• Hydrochlorothiazide is a thiazide diuretic (water pill) canadian prescriptions hyzaar. It increasesthe amount of water and salt you lose in your urine canadian prescriptions hyzaar. Hydrochlorothiazide isused to lower blood pressure and to decrease edema (swelling) canadian prescriptions hyzaar.
• Hyzaar is used to reduce hypertension (high blood pressure) canadian prescriptions hyzaar.
• Hyzaar may also be used for purposes other than those listed in thismedication guide canadian prescriptions hyzaar.


Who should not take Hyzaar?
• Do not take Hyzaar without first talking to your doctor if you have anallergy to sulfa-based drugs such as sulfa antibiotics canadian prescriptions hyzaar. You may have an allergicreaction to hydrochlorothiazide canadian prescriptions hyzaar.
• Before taking Hyzaar, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have any type of heart disease or have had a stroke;
· are on a salt-restricted diet or have high levels of potassium in yourblood; or
· are taking potassium supplements (e.g., K-Dur, Klor-Con, others), ora potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) canadian prescriptions hyzaar.
• You may not be able to take Hyzaar, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove canadian prescriptions hyzaar.
• Hyzaar is in the FDA pregnancy category D canadian prescriptions hyzaar. This means that it is knownto harm an unborn baby canadian prescriptions hyzaar. When used during the second and third trimesters ofpregnancy, losartan can cause injury and even death of the developing fetus canadian prescriptions hyzaar. Do not take this medication if you are pregnant canadian prescriptions hyzaar.
• It is not known whether this drug passes into breast milk canadian prescriptions hyzaar. Do not takeHyzaar without first talking to your doctor if you are breast-feeding a baby canadian prescriptions hyzaar.


How should I take Hyzaar?
• Take Hyzaar exactly as directed by your doctor canadian prescriptions hyzaar. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you canadian prescriptions hyzaar.
• Take each dose with a full glass (8 ounces) of water canadian prescriptions hyzaar.
• You can take Hyzaar with or without food canadian prescriptions hyzaar.
• Do not stop taking this medication without first talking to your doctor canadian prescriptions hyzaar. If you stop taking this medication, your condition could become worse canadian prescriptions hyzaar.
• Call your doctor before taking any more doses if you develop severe dizzinessor fainting canadian prescriptions hyzaar.
• Store Hyzaar at room temperature away from moisture and heat canadian prescriptions hyzaar.


What happens if I miss a dose?
• Take the missed dose as soon as you remember canadian prescriptions hyzaar. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose canadian prescriptions hyzaar. Do not take a double dose of this medication canadian prescriptions hyzaar.


What happens if I overdose?
• Seek emergency medical attention canadian prescriptions hyzaar.
• Symptoms of a Hyzaar overdose are not well known but may include dizziness,weakness, fainting, and fatigue canadian prescriptions hyzaar.


What should I avoid while taking Hyzaar?
• Use caution when driving, operating machinery, or performing other hazardousactivities canadian prescriptions hyzaar. Hyzaar may cause dizziness or drowsiness canadian prescriptions hyzaar. If you experience dizzinessor drowsiness, avoid these activities canadian prescriptions hyzaar. Also use caution when rising from a sittingor lying position canadian prescriptions hyzaar.
• Use alcohol cautiously canadian prescriptions hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar canadian prescriptions hyzaar.
• Avoid a diet high in salt canadian prescriptions hyzaar. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide canadian prescriptions hyzaar.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor canadian prescriptions hyzaar. Losartan can affect potassium levels in your body canadian prescriptions hyzaar.
• Avoid prolonged exposure to sunlight canadian prescriptions hyzaar. Hyzaar may increase the sensitivityof your skin to sunlight canadian prescriptions hyzaar. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable canadian prescriptions hyzaar.
• Avoid becoming overheated in hot weather canadian prescriptions hyzaar. It is easy to become dangerouslydehydrated while taking hydrochlorothiazide canadian prescriptions hyzaar.


What are the possible side effects of Hyzaar?
• If you experience any of the following serious side effects, stop takingHyzaar and call your doctor immediately or seek emergency medical treatment canadian prescriptions hyzaar.
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes, confusion; or
· fainting canadian prescriptions hyzaar.
• Other, less serious side effects may be more likely to occur canadian prescriptions hyzaar. Continueto take Hyzaar and talk to your doctor if you experience
· diarrhea or upset stomach;
· muscle pain or cramps;
· dizziness;
· insomnia;
· congestion or cough;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite; or
· sensitivity to sunlight canadian prescriptions hyzaar.
• Side effects other than those listed here may also occur canadian prescriptions hyzaar. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome canadian prescriptions hyzaar.


What other drugs will affect Hyzaar?
• Before taking Hyzaar, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a barbiturate such as phenobarbital (Luminal, Solfoton), pentobarbital(Nembutal), secobarbital (Seconal), mephobarbital (Mebaral), and others;
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) canadian prescriptions hyzaar.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above canadian prescriptions hyzaar.
• Drugs other than those listed here may also interact with Hyzaar or affectyour condition canadian prescriptions hyzaar. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines canadian prescriptions hyzaar.


Where can I get more information?
• Your pharmacist has additional information about Hyzaar written for healthprofessionals that you may read canadian prescriptions hyzaar.


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