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problems found taking hyzaar
losartan and hydrochlorothiazide (low SAR tan and hye droe klor oh THYE a zide)

What is the most important information I should know about Hyzaar?
• Do not take Hyzaar if you are pregnant or planning a pregnancy problems found taking hyzaar. Whenused during the second and third trimesters of pregnancy, losartan can causeinjury and even death to the developing fetus problems found taking hyzaar. Notify your doctor immediatelyif you think you might be pregnant problems found taking hyzaar.
• Use caution when driving, operating machinery, or performing other hazardousactivities problems found taking hyzaar. Hyzaar may cause dizziness or drowsiness problems found taking hyzaar. If you experience dizzinessor drowsiness, avoid these activities problems found taking hyzaar. Also use caution when rising from a sittingor lying position problems found taking hyzaar.
• Use alcohol cautiously problems found taking hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar problems found taking hyzaar.


What is Hyzaar?
• Losartan is in a class of drugs called angiotensin II receptor antagonists problems found taking hyzaar.
• Hydrochlorothiazide is a thiazide diuretic (water pill) problems found taking hyzaar. It increasesthe amount of water and salt you lose in your urine problems found taking hyzaar. Hydrochlorothiazide isused to lower blood pressure and to decrease edema (swelling) problems found taking hyzaar.
• Hyzaar is used to reduce hypertension (high blood pressure) problems found taking hyzaar.
• Hyzaar may also be used for purposes other than those listed in thismedication guide problems found taking hyzaar.


Who should not take Hyzaar?
• Do not take Hyzaar without first talking to your doctor if you have anallergy to sulfa-based drugs such as sulfa antibiotics problems found taking hyzaar. You may have an allergicreaction to hydrochlorothiazide problems found taking hyzaar.
• Before taking Hyzaar, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have any type of heart disease or have had a stroke;
· are on a salt-restricted diet or have high levels of potassium in yourblood; or
· are taking potassium supplements (e.g., K-Dur, Klor-Con, others), ora potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) problems found taking hyzaar.
• You may not be able to take Hyzaar, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove problems found taking hyzaar.
• Hyzaar is in the FDA pregnancy category D problems found taking hyzaar. This means that it is knownto harm an unborn baby problems found taking hyzaar. When used during the second and third trimesters ofpregnancy, losartan can cause injury and even death of the developing fetus problems found taking hyzaar. Do not take this medication if you are pregnant problems found taking hyzaar.
• It is not known whether this drug passes into breast milk problems found taking hyzaar. Do not takeHyzaar without first talking to your doctor if you are breast-feeding a baby problems found taking hyzaar.


How should I take Hyzaar?
• Take Hyzaar exactly as directed by your doctor problems found taking hyzaar. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you problems found taking hyzaar.
• Take each dose with a full glass (8 ounces) of water problems found taking hyzaar.
• You can take Hyzaar with or without food problems found taking hyzaar.
• Do not stop taking this medication without first talking to your doctor problems found taking hyzaar. If you stop taking this medication, your condition could become worse problems found taking hyzaar.
• Call your doctor before taking any more doses if you develop severe dizzinessor fainting problems found taking hyzaar.
• Store Hyzaar at room temperature away from moisture and heat problems found taking hyzaar.


What happens if I miss a dose?
• Take the missed dose as soon as you remember problems found taking hyzaar. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose problems found taking hyzaar. Do not take a double dose of this medication problems found taking hyzaar.


What happens if I overdose?
• Seek emergency medical attention problems found taking hyzaar.
• Symptoms of a Hyzaar overdose are not well known but may include dizziness,weakness, fainting, and fatigue problems found taking hyzaar.


What should I avoid while taking Hyzaar?
• Use caution when driving, operating machinery, or performing other hazardousactivities problems found taking hyzaar. Hyzaar may cause dizziness or drowsiness problems found taking hyzaar. If you experience dizzinessor drowsiness, avoid these activities problems found taking hyzaar. Also use caution when rising from a sittingor lying position problems found taking hyzaar.
• Use alcohol cautiously problems found taking hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar problems found taking hyzaar.
• Avoid a diet high in salt problems found taking hyzaar. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide problems found taking hyzaar.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor problems found taking hyzaar. Losartan can affect potassium levels in your body problems found taking hyzaar.
• Avoid prolonged exposure to sunlight problems found taking hyzaar. Hyzaar may increase the sensitivityof your skin to sunlight problems found taking hyzaar. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable problems found taking hyzaar.
• Avoid becoming overheated in hot weather problems found taking hyzaar. It is easy to become dangerouslydehydrated while taking hydrochlorothiazide problems found taking hyzaar.


What are the possible side effects of Hyzaar?
• If you experience any of the following serious side effects, stop takingHyzaar and call your doctor immediately or seek emergency medical treatment problems found taking hyzaar.
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes, confusion; or
· fainting problems found taking hyzaar.
• Other, less serious side effects may be more likely to occur problems found taking hyzaar. Continueto take Hyzaar and talk to your doctor if you experience
· diarrhea or upset stomach;
· muscle pain or cramps;
· dizziness;
· insomnia;
· congestion or cough;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite; or
· sensitivity to sunlight problems found taking hyzaar.
• Side effects other than those listed here may also occur problems found taking hyzaar. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome problems found taking hyzaar.


What other drugs will affect Hyzaar?
• Before taking Hyzaar, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a barbiturate such as phenobarbital (Luminal, Solfoton), pentobarbital(Nembutal), secobarbital (Seconal), mephobarbital (Mebaral), and others;
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) problems found taking hyzaar.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above problems found taking hyzaar.
• Drugs other than those listed here may also interact with Hyzaar or affectyour condition problems found taking hyzaar. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines problems found taking hyzaar.


Where can I get more information?
• Your pharmacist has additional information about Hyzaar written for healthprofessionals that you may read problems found taking hyzaar.


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