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side effect of medication hyzaar
losartan and hydrochlorothiazide (low SAR tan and hye droe klor oh THYE a zide)

What is the most important information I should know about Hyzaar?
• Do not take Hyzaar if you are pregnant or planning a pregnancy side effect of medication hyzaar. Whenused during the second and third trimesters of pregnancy, losartan can causeinjury and even death to the developing fetus side effect of medication hyzaar. Notify your doctor immediatelyif you think you might be pregnant side effect of medication hyzaar.
• Use caution when driving, operating machinery, or performing other hazardousactivities side effect of medication hyzaar. Hyzaar may cause dizziness or drowsiness side effect of medication hyzaar. If you experience dizzinessor drowsiness, avoid these activities side effect of medication hyzaar. Also use caution when rising from a sittingor lying position side effect of medication hyzaar.
• Use alcohol cautiously side effect of medication hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar side effect of medication hyzaar.


What is Hyzaar?
• Losartan is in a class of drugs called angiotensin II receptor antagonists side effect of medication hyzaar.
• Hydrochlorothiazide is a thiazide diuretic (water pill) side effect of medication hyzaar. It increasesthe amount of water and salt you lose in your urine side effect of medication hyzaar. Hydrochlorothiazide isused to lower blood pressure and to decrease edema (swelling) side effect of medication hyzaar.
• Hyzaar is used to reduce hypertension (high blood pressure) side effect of medication hyzaar.
• Hyzaar may also be used for purposes other than those listed in thismedication guide side effect of medication hyzaar.


Who should not take Hyzaar?
• Do not take Hyzaar without first talking to your doctor if you have anallergy to sulfa-based drugs such as sulfa antibiotics side effect of medication hyzaar. You may have an allergicreaction to hydrochlorothiazide side effect of medication hyzaar.
• Before taking Hyzaar, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have any type of heart disease or have had a stroke;
· are on a salt-restricted diet or have high levels of potassium in yourblood; or
· are taking potassium supplements (e.g., K-Dur, Klor-Con, others), ora potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) side effect of medication hyzaar.
• You may not be able to take Hyzaar, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove side effect of medication hyzaar.
• Hyzaar is in the FDA pregnancy category D side effect of medication hyzaar. This means that it is knownto harm an unborn baby side effect of medication hyzaar. When used during the second and third trimesters ofpregnancy, losartan can cause injury and even death of the developing fetus side effect of medication hyzaar. Do not take this medication if you are pregnant side effect of medication hyzaar.
• It is not known whether this drug passes into breast milk side effect of medication hyzaar. Do not takeHyzaar without first talking to your doctor if you are breast-feeding a baby side effect of medication hyzaar.


How should I take Hyzaar?
• Take Hyzaar exactly as directed by your doctor side effect of medication hyzaar. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you side effect of medication hyzaar.
• Take each dose with a full glass (8 ounces) of water side effect of medication hyzaar.
• You can take Hyzaar with or without food side effect of medication hyzaar.
• Do not stop taking this medication without first talking to your doctor side effect of medication hyzaar. If you stop taking this medication, your condition could become worse side effect of medication hyzaar.
• Call your doctor before taking any more doses if you develop severe dizzinessor fainting side effect of medication hyzaar.
• Store Hyzaar at room temperature away from moisture and heat side effect of medication hyzaar.


What happens if I miss a dose?
• Take the missed dose as soon as you remember side effect of medication hyzaar. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose side effect of medication hyzaar. Do not take a double dose of this medication side effect of medication hyzaar.


What happens if I overdose?
• Seek emergency medical attention side effect of medication hyzaar.
• Symptoms of a Hyzaar overdose are not well known but may include dizziness,weakness, fainting, and fatigue side effect of medication hyzaar.


What should I avoid while taking Hyzaar?
• Use caution when driving, operating machinery, or performing other hazardousactivities side effect of medication hyzaar. Hyzaar may cause dizziness or drowsiness side effect of medication hyzaar. If you experience dizzinessor drowsiness, avoid these activities side effect of medication hyzaar. Also use caution when rising from a sittingor lying position side effect of medication hyzaar.
• Use alcohol cautiously side effect of medication hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar side effect of medication hyzaar.
• Avoid a diet high in salt side effect of medication hyzaar. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide side effect of medication hyzaar.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor side effect of medication hyzaar. Losartan can affect potassium levels in your body side effect of medication hyzaar.
• Avoid prolonged exposure to sunlight side effect of medication hyzaar. Hyzaar may increase the sensitivityof your skin to sunlight side effect of medication hyzaar. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable side effect of medication hyzaar.
• Avoid becoming overheated in hot weather side effect of medication hyzaar. It is easy to become dangerouslydehydrated while taking hydrochlorothiazide side effect of medication hyzaar.


What are the possible side effects of Hyzaar?
• If you experience any of the following serious side effects, stop takingHyzaar and call your doctor immediately or seek emergency medical treatment side effect of medication hyzaar.
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes, confusion; or
· fainting side effect of medication hyzaar.
• Other, less serious side effects may be more likely to occur side effect of medication hyzaar. Continueto take Hyzaar and talk to your doctor if you experience
· diarrhea or upset stomach;
· muscle pain or cramps;
· dizziness;
· insomnia;
· congestion or cough;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite; or
· sensitivity to sunlight side effect of medication hyzaar.
• Side effects other than those listed here may also occur side effect of medication hyzaar. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome side effect of medication hyzaar.


What other drugs will affect Hyzaar?
• Before taking Hyzaar, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a barbiturate such as phenobarbital (Luminal, Solfoton), pentobarbital(Nembutal), secobarbital (Seconal), mephobarbital (Mebaral), and others;
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) side effect of medication hyzaar.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above side effect of medication hyzaar.
• Drugs other than those listed here may also interact with Hyzaar or affectyour condition side effect of medication hyzaar. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines side effect of medication hyzaar.


Where can I get more information?
• Your pharmacist has additional information about Hyzaar written for healthprofessionals that you may read side effect of medication hyzaar.


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