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side effects from hyzaar
losartan and hydrochlorothiazide (low SAR tan and hye droe klor oh THYE a zide)

What is the most important information I should know about Hyzaar?
• Do not take Hyzaar if you are pregnant or planning a pregnancy side effects from hyzaar. Whenused during the second and third trimesters of pregnancy, losartan can causeinjury and even death to the developing fetus side effects from hyzaar. Notify your doctor immediatelyif you think you might be pregnant side effects from hyzaar.
• Use caution when driving, operating machinery, or performing other hazardousactivities side effects from hyzaar. Hyzaar may cause dizziness or drowsiness side effects from hyzaar. If you experience dizzinessor drowsiness, avoid these activities side effects from hyzaar. Also use caution when rising from a sittingor lying position side effects from hyzaar.
• Use alcohol cautiously side effects from hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar side effects from hyzaar.


What is Hyzaar?
• Losartan is in a class of drugs called angiotensin II receptor antagonists side effects from hyzaar.
• Hydrochlorothiazide is a thiazide diuretic (water pill) side effects from hyzaar. It increasesthe amount of water and salt you lose in your urine side effects from hyzaar. Hydrochlorothiazide isused to lower blood pressure and to decrease edema (swelling) side effects from hyzaar.
• Hyzaar is used to reduce hypertension (high blood pressure) side effects from hyzaar.
• Hyzaar may also be used for purposes other than those listed in thismedication guide side effects from hyzaar.


Who should not take Hyzaar?
• Do not take Hyzaar without first talking to your doctor if you have anallergy to sulfa-based drugs such as sulfa antibiotics side effects from hyzaar. You may have an allergicreaction to hydrochlorothiazide side effects from hyzaar.
• Before taking Hyzaar, tell your doctor if you
· have diabetes;
· have gout;
· have a collagen vascular disease such as systemic lupus erythematosus;
· have pancreatitis;
· have kidney disease;
· have liver disease;
· have any type of heart disease or have had a stroke;
· are on a salt-restricted diet or have high levels of potassium in yourblood; or
· are taking potassium supplements (e.g., K-Dur, Klor-Con, others), ora potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone) side effects from hyzaar.
• You may not be able to take Hyzaar, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove side effects from hyzaar.
• Hyzaar is in the FDA pregnancy category D side effects from hyzaar. This means that it is knownto harm an unborn baby side effects from hyzaar. When used during the second and third trimesters ofpregnancy, losartan can cause injury and even death of the developing fetus side effects from hyzaar. Do not take this medication if you are pregnant side effects from hyzaar.
• It is not known whether this drug passes into breast milk side effects from hyzaar. Do not takeHyzaar without first talking to your doctor if you are breast-feeding a baby side effects from hyzaar.


How should I take Hyzaar?
• Take Hyzaar exactly as directed by your doctor side effects from hyzaar. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you side effects from hyzaar.
• Take each dose with a full glass (8 ounces) of water side effects from hyzaar.
• You can take Hyzaar with or without food side effects from hyzaar.
• Do not stop taking this medication without first talking to your doctor side effects from hyzaar. If you stop taking this medication, your condition could become worse side effects from hyzaar.
• Call your doctor before taking any more doses if you develop severe dizzinessor fainting side effects from hyzaar.
• Store Hyzaar at room temperature away from moisture and heat side effects from hyzaar.


What happens if I miss a dose?
• Take the missed dose as soon as you remember side effects from hyzaar. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose side effects from hyzaar. Do not take a double dose of this medication side effects from hyzaar.


What happens if I overdose?
• Seek emergency medical attention side effects from hyzaar.
• Symptoms of a Hyzaar overdose are not well known but may include dizziness,weakness, fainting, and fatigue side effects from hyzaar.


What should I avoid while taking Hyzaar?
• Use caution when driving, operating machinery, or performing other hazardousactivities side effects from hyzaar. Hyzaar may cause dizziness or drowsiness side effects from hyzaar. If you experience dizzinessor drowsiness, avoid these activities side effects from hyzaar. Also use caution when rising from a sittingor lying position side effects from hyzaar.
• Use alcohol cautiously side effects from hyzaar. Alcohol may further lower blood pressure andincrease drowsiness and dizziness while you are taking Hyzaar side effects from hyzaar.
• Avoid a diet high in salt side effects from hyzaar. Too much salt may cause your body to retainwater and may decrease the effects of hydrochlorothiazide side effects from hyzaar.
• Do not use salt substitutes or take potassium supplements without firsttalking to your doctor side effects from hyzaar. Losartan can affect potassium levels in your body side effects from hyzaar.
• Avoid prolonged exposure to sunlight side effects from hyzaar. Hyzaar may increase the sensitivityof your skin to sunlight side effects from hyzaar. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable side effects from hyzaar.
• Avoid becoming overheated in hot weather side effects from hyzaar. It is easy to become dangerouslydehydrated while taking hydrochlorothiazide side effects from hyzaar.


What are the possible side effects of Hyzaar?
• If you experience any of the following serious side effects, stop takingHyzaar and call your doctor immediately or seek emergency medical treatment side effects from hyzaar.
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· little or no urine;
· unusual fatigue, abnormal bleeding or bruising;
· yellow skin or eyes, confusion; or
· fainting side effects from hyzaar.
• Other, less serious side effects may be more likely to occur side effects from hyzaar. Continueto take Hyzaar and talk to your doctor if you experience
· diarrhea or upset stomach;
· muscle pain or cramps;
· dizziness;
· insomnia;
· congestion or cough;
· tingling or numbness in your arms, legs, hands, or feet;
· excessive urination;
· muscle weakness or cramps;
· increased hunger or thirst;
· nausea or decreased appetite; or
· sensitivity to sunlight side effects from hyzaar.
• Side effects other than those listed here may also occur side effects from hyzaar. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome side effects from hyzaar.


What other drugs will affect Hyzaar?
• Before taking Hyzaar, tell your doctor if you are taking
· a potassium supplement such as K-Dur, Klor-Con, and others;
· a potassium-sparing diuretic (water pill) such as amiloride (Midamor),spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
· a barbiturate such as phenobarbital (Luminal, Solfoton), pentobarbital(Nembutal), secobarbital (Seconal), mephobarbital (Mebaral), and others;
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam,Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro),naproxen (Naprosyn, Anaprox, Aleve), and others;
· an oral diabetes medication such as glipizide (Glucotrol), glyburide(Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase),or tolbutamide (Orinase);
· cholestyramine (Questran) or colestipol (Colestid);
· lithium (Lithobid, Eskalith, others); or
· digoxin (Lanoxin) side effects from hyzaar.
• You may require a dosage adjustment or special monitoring during treatmentif you are taking any of the medicines listed above side effects from hyzaar.
• Drugs other than those listed here may also interact with Hyzaar or affectyour condition side effects from hyzaar. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines side effects from hyzaar.


Where can I get more information?
• Your pharmacist has additional information about Hyzaar written for healthprofessionals that you may read side effects from hyzaar.


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